Alan N Engelman Selected Research

gag-pol Fusion Proteins

12/2019

Disrupting MLV integrase:BET protein interaction biases integration into quiescent chromatin and delays but does not eliminate tumor activation in a MYC/Runx2 mouse model.

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Alan N Engelman Research Topics

Disease

9	Infections 07/2022 - 10/2015
7	Acquired Immunodeficiency Syndrome (AIDS) 07/2022 - 01/2016
2	Virus Diseases (Viral Diseases) 12/2021 - 11/2019
2	Neoplasms (Cancer) 12/2019 - 01/2015
2	HIV Infections (HIV Infection) 10/2019 - 12/2017
1	Viremia 07/2022
1	Carcinogenesis 12/2019
1	Communicable Diseases (Infectious Diseases) 01/2015

Drug/Important Bio-Agent (IBA)

5	Proteins (Proteins, Gene)FDA Link 07/2022 - 12/2017
5	IntegrasesIBA 12/2020 - 10/2015
2	Antiviral Agents (Antivirals)IBA 07/2022 - 01/2020
2	ChromatinIBA 01/2021 - 12/2019
2	EnzymesIBA 12/2020 - 10/2019
2	lens epithelium-derived growth factorIBA 11/2016 - 01/2015
2	DNA (Deoxyribonucleic Acid)IBA 01/2016 - 10/2015
1	PhosphoproteinsIBA 07/2022
1	Histone Acetyltransferases (Histone Acetyltransferase)IBA 07/2022
1	Amino Acids FDA Link 12/2021
1	Cyclophilin AIBA 01/2021
1	Cleavage And Polyadenylation Specificity FactorIBA 01/2021
1	cabotegravirIBA 01/2021
1	Capsid Proteins (Capsid Protein)IBA 01/2020
1	IonsIBA 01/2020
1	MagnesiumIBA 01/2020
1	gag-pol Fusion ProteinsIBA 12/2019
1	RNA-Directed DNA Polymerase (Reverse Transcriptase)IBA 10/2019
1	Peptide Hydrolases (Proteases)FDA Link 10/2019
1	Integrase InhibitorsIBA 10/2019
1	Nucleic AcidsIBA 12/2017
1	Antiviral Restriction FactorsIBA 01/2017
1	Pharmaceutical PreparationsIBA 10/2016
1	RNA (Ribonucleic Acid)IBA 01/2016
1	Viral RNAIBA 10/2015
1	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 01/2015

Therapy/Procedure

3	Therapeutics 07/2022 - 01/2020
1	Art Therapy 01/2016